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Transcript of 'Mode of Action' Presentation
The following is a transcript of the flash presentation on the mode
of action of RECALDENT™ (CPP-ACP)
Visual: The presentation is contained
within a pale green ellipse. Four icons move in from the left, they are: a person brushing
teeth, a person flossing, bottle of mouth wash, person at the dentist.
Most people know the basics of oral health care - brushing, flossing, rinsing
and regular visits to your Dentist and Hygienist. However, oral health care
professionals are learning about an important step forward in the field
of oral health.
Visual: A three-dimensional drawing of a tooth
with the word Demineralization. There are Calcium and Phosphate
ions moving out of the tooth.
The first stage of tooth decay is demineralization - where the tooth enamel
is weakened through the loss of the minerals Calcium and Phosphate. If allowed
to progress, the decay can extend into the dentin and eventually into the
pulp of the tooth, requiring treatment from your dentist.
Visual: The same tooth with the word Remineralization. There are Calcium
and Phosphate ions moving into the tooth.
Recaldent™ is a new patented technology that works to reverse the effects
of demineralization by remineralizing - replacing the lost Calcium and Phosphate
and rebuilding the tooth enamel.
Visual: A cross section of
the tooth with the three parts, an arrow shows the enamel on the
outside, the dentin in the middle and the pulp on the inside of the tooth.
To understand what happens during demineralization and remineralization,
let's look at the anatomy of the tooth.
The tooth is made up of three parts. The enamel, the dentin and the pulp.
Visual: The tooth cross section moves in to closer view. A magnified
circle shows a section of outer enamel and dentin.
Enamel is the hard tissue which appears above the gum and consists primarily
of the minerals Calcium and Phosphate.
Visual: The magnified circle focuses on the white enamel with many tiny white rods packed closely
together.
The Calcium and Phosphate combine to form crystals. These crystals arrange
themselves to form millions of tiny rods packed closely together.
The enamel is resistant to heat and most liquids, but acids can break it
down.
Visual: The magnified circle now focuses on the yellow dentin.
Dentin is the softer tissue under the enamel crown. It's made up of minerals
and organic matter.
Visual: The magnified circle now focuses on red-brown pulp.
The sensitive pulp in the centre of the tooth contains blood supply and
nerves.
Visual: Magnified circle disappears. The cross section
of the tooth has an animated, brown tear-drop area of decay spreading
from the enamel surface and into the dentin.
Tooth decay, also known as dental caries, starts with the demineralization
of the enamel by organic acids.
Visual: The tooth moves into
closer view with the area of decay at the surface of
the enamel. Bacteria are represented by grey bean shapes on the tooth surface.
Sugar cubes move down into the bacteria, and green H+ acid spheres are emitted
from the bacteria and onto the tooth surface.
The bacteria found in dental plaque ferments sugars and other carbohydrates
from the diet, producing organic acids, shown here as H+.
Visual: The Enamel rods with the green acid spheres moving into the rods
and causing decay spots to appear.
Calcium and Phosphate ions are moving out of the rods.
Although the enamel rods are packed
tightly together, the acids enter and dissolve the Calcium Phosphate crystals,
releasing Calcium and Phosphate ions which move out of the enamel into the
saliva.
This process is known as demineralization.
Visual: The tooth cross section is now in more distant view with the enamel,
dentin and pulp. The brown tear-drop decay area moves from the surface of the tooth
and into the pulp. When it reaches the pulp a flashing red shape appears to
represent pain.
Left unchecked, this decay process can progress through the enamel into
the dentin and the pulp, resulting in pain and requiring treatment by the
dentist.
Visual: A close-up view of the enamel rods with Calcium and Phosphate
ions moving into the rods.
Remineralization is the reverse of this process - where the Calcium and
Phosphate ions move back into the demineralized areas of the enamel.
Let's look at how Recaldent™ promotes the remineralization process.
Visual: Tooth moves to show the enamel at the surface. The grey bean-shaped
bacteria move onto the tooth surface, then the CPP-ACP ellipses
move in to cover the bacteria
Recaldent™ first binds to the dental plaque creating a high concentration
of Calcium and Phosphate ions.
Visual: A close-up of the enamel rods with the CPP-ACP ellipses
on the surface. Calcium and Phosphate ions move from the ellipses to the rods.
Because of their high concentration, these ions move into the space between
the rods leaving the peptides bound to the plaque.
Without the peptides the ions reform into crystals,which then restore the
rods.
Visual: Calcium and Phosphate ions move out of the word
Demineralization and into the word Remineralization.
The text "Demineralization = higher rates of decay" is shown
followed by "Remineralization = strong enamel"
The process of demineralization and remineralization alternates throughout
the day.
Visual: Images of some Recaldent™ products grouped together:
Trident White; Coolmint Gum; Trident for Kids; Trident Advantage.
These products are also shown on the
Where can I find Recaldent™ page
You can find Recaldent™ in these great oral care products.
And watch for Recaldent™ with proven remineralizing activity in the oral
health products of the future.
Visual: Recaldent™ logo. |
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